Preheat oven to 375
Spray 9x13 glass casserole dish with non stick spray
Open one tube of dough unroll flat and pinch together all the seams
Sprinkle with half the Italian seasoning
Layer half the ham, leaving about 3/4-1' space each end of the dough
Layer half the provolone cheese over the ham
Place half the pepperoni in four rows of 5, equally spaced
Sprinkle with half the shredded mozzarella and cheddar
Carefully roll from the short end, sealing any cracks as you go and sealing the last end to the roll when it's done
Slice the roll in to six pieces
Repeat with the other can of dough and the other half of the ingredients - you will have 12 rolls total
Place rolls equally spaced in 4 rows of 3 in prepared pan
In a small bowl, whisk together the melted margarine, dijon mustard, honey, poppy seeds, onion powder and Worcestershire sauce
Spoon the butter mixture over the top of each roll
Bake at 375 for 30-35 minutes